In March 2021, the CBTDDC launched the Clinical Trials Working Group for CNS Drug Delivery. This group has identified the main challenges in preclinical to clinical translation of paediatric CNS drug delivery devices as:
- a lack of specific funding for prototype development and/or scale-up for clinical trials;
- difficulties in navigating the regulatory landscape;
- lack of accurate preclinical models; and
- increased need for multicentric working.
On 8-9 November 2021, we hosted a ‘Clinical Trial Readiness for CNS Drug Delivery’ workshop to tackle these challenges, with the ultimate aim of creating a ‘Roadmap’ document for preclinical to clinical translation that we can share widely with the neuro-oncology community.
Programme for the day
See the programme for the Nottingham 2021 Workshop here.
We are currently compiling this information. Some of the data presented was confidential so cannot be shared.
Pump Prime Funding Call
We opened a £40k Pump Prime funding call at the workshop. Delegates were invited to submit bids for projects (up to a maximum of £10k each) that will address challenges along the preclinical to clinical pathway to move trial proposals into an ‘advanced state of readiness’. Read the call guidelines here.
Summary of workshop
This will be available over the coming weeks.