Topham, Caroline

Principal Investigator

University of Salford, UK

Improving efficacy of anti-mitotic chemotherapy for treatment of medulloblastoma

We are interested in understanding how molecular heterogeneity in medulloblastoma may be linked to functional heterogeneity, in terms of sensitivity/resistance to vincristine. Through this work we have identified a potential strategy for sensitization of medulloblastoma lines using a combination treatment, but this second treatment cannot cross the blood-brain barrier. We are therefore interested in making links with researchers with expertise in modes of drug delivery to circumvent this.

Existing collaborations relevant to drug delivery


Publications relevant to drug delivery


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