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In vitro modelling of the blood-brain barrier and blood-tumor barrier using human cells, to study the BBB properties in a cancer environment and its consequences on the delivery of chemotherapeutic drugs to the brain. 

Existing collaborations relevant to drug delivery

Marina Resmini, Professor of Materials Chemistry, Head of Chemistry Department, School of Biological and Chemical Sciences, Queen Mary University of London.

Publications relevant to drug delivery

Deligne C, Hachani J, Duban-Deweer S, Meignan S, Leblond P, Carcaboso AM, Sano Y, Shimizu F, Kanda T, Gosselet F, Dehouck MP, Mysiorek C. Development of a human in vitro blood-brain tumor barrier model of diffuse intrinsic pontine glioma to better understand the chemoresistance. Fluids Barriers CNS. 2020 Jun 2;17(1):37. doi: 10.1186/s12987-020-00198-0. PMID: 32487241; PMCID: PMC7268424.