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I have been working on understanding the infusion mechanisms in CNS tissue and its microscale mechanical behaviour using experimental techniques. This is important for the optimisation of infusion-based drug delivery therapies such as convection-enhanced delivery. I have recently revealed that drug-infusion in CNS tissue is significantly dependent on the directionality of axons.

Existing collaborations relevant to drug delivery

N/A

Publications relevant to drug delivery

A. Jamal et al. Infusion Mechanisms in Brain White Matter and its Dependence of Microstructure: An Experimental Study of Hydraulic Permeability, IEEE TBME, Volume: 68, Issue: 4, April 2021. DOI: 10.1109/TBME.2020.3024117