Grundy, Richard

Professor of Neuro-Oncology and Cancer Biology / Co-Director CBTRC

University of Nottingham, UK

Children's Brain Tumour Research Centre (CBTRC)

My expertise is in molecular neuro-oncology, functional imaging, biomarkers, localised drug delivery and clinical trials. In particular, I have significant expertise in intraventricular chemotherapy predominantly using etoposide. I am also chief UK investigator for the SIOP ependymoma II trial.

Tumour type: Ependymoma, High Grade Glioma, Medulloblastoma. 

Existing collaborations relevant to drug delivery

Prof. Henry Brem and Dr. Betty Tyler (Johns Hopkins Medical School) – Evaluation of polymer-based chemotherapy delivery using neurosurgical orthotopic high grade glioma models. 

Publications relevant to drug delivery

Smith SJ, … Grundy RG, Rahman R. Surgical delivery of drug-releasing poly(lactic-co-glycolic acid) / poly(ethylene glycol) paste with in vivo effects against glioblastoma. Annals of Royal College of Surgeons England 96: 495-501 (2014).  

Rahman CV, … Grundy RG, Rahman R.  Adjuvant chemotherapy for brain tumours delivered via a novel intra-cavity mouldable polymer matrix. PLoS One 8(10): e77435 (2013). 

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