Evans, Stephen

University of Leeds, UK

Expertise in:

1. Developing Therapeutic Microbubbles, as theranostic agents, for enhanced, targeted drug delivery to cancers.

2. Nanobubble loaded Liposomes for Drug Delivery




Existing collaborations relevant to drug delivery

AF Markham, PL Coletta : preclinical models for colorectal cancer

S Freear, J Mclaughlin Ultrasound based bubble disruption

Publications relevant to drug delivery

Roach L, Ye SJ, Moorcroft SCT, Critchley K, Coletta PL, Evans SD. Morphological control of seedlessly-synthesized gold nanorods using binary surfactants. Nanotechnology. 2018;29(13).

Churchman AH, Mico V, de Pablo JG, Peyman SA, Freear S, Evans SD. Combined flow-focus and self-assembly routes for the formation of lipid stabilized oil-shelled microbubbles. Microsystems & Nanoengineering. 2018;4.

Alataki A, Abou-Saleh R, McLaughlan JR, Markham AF, Evans SD, Coletta PL, et al. Developing targeted therapeutic microbubbles for enhanced epigenetic drug delivery for breast cancer. Cancer Research. 2018;78(4).

Mico V, Charalambous A, Peyman SA, Abou-Saleh RH, Markham AF, et al. Evaluation of lipid-stabilised tripropionin nanodroplets as a delivery route for combretastatin A4. Int J Pharm. 2017;526(1-2):547-555.

Kong Y, Chen J, et al. Highly fluorescent ribonuclease-A-encapsulated lead sulfide quantum dots for ultrasensitive fluorescence in vivo imaging in the second near-infrared window. Chemistry of Materials 2017, 28 (9), 3041-3050

Peyman SA, McLaughlan JR, Abou-Saleh RH, Marston G, Johnson BR, Freear S, et al. On-chip preparation of nanoscale contrast agents towards high-resolution ultrasound imaging. Lab Chip. 2016;16(4):679-687.

Ye SJ, Marston G, McLaughlan JR, Sigle DO, Ingram N, Freear S, et al. Engineering Gold Nanotubes with Controlled Length and Near-Infrared Absorption for Theranostic Applications. Advanced Functional Materials. 2015;25(14):2117-2127.

Abou-Saleh RH, Swain M, Evans SD, Thomson NH. Poly(ethylene glycol) lipid-shelled microbubbles: abundance, stability, and mechanical properties. Langmuir. 2014;30(19):5557-5563.

Bencsik M, Al-Rwaili A, Morris R, Fairhurst DJ, Mundell V, Cave G, et al. Quantitation of MRI sensitivity to quasi-monodisperse microbubble contrast agents for spatially resolved manometry. Magn Reson Med. 2013;70(5):1409-1418.

Abou-Saleh RH, Peyman SA, Critchley K, Evans SD, Thomson NH. Nanomechanics of lipid encapsulated microbubbles with functional coatings. Langmuir. 2013;29(12):4096-4103.

Peyman SA, Abou-Saleh RH, McLaughlan JR, Ingram N, Johnson BR, Critchley K, et al. Expanding 3D geometry for enhanced on-chip microbubble production and single step formation of liposome modified microbubbles. Lab Chip. 2012;12(21):4544-4552.

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