University of Leeds, UK
1. Developing Therapeutic Microbubbles, as theranostic agents, for enhanced, targeted drug delivery to cancers.
2. Nanobubble loaded Liposomes for Drug Delivery
EPSRC, BBSRC and MRC.
Existing collaborations relevant to drug delivery
AF Markham, PL Coletta : preclinical models for colorectal cancer
S Freear, J Mclaughlin Ultrasound based bubble disruption
Publications relevant to drug delivery
Roach L, Ye SJ, Moorcroft SCT, Critchley K, Coletta PL, Evans SD. Morphological control of seedlessly-synthesized gold nanorods using binary surfactants. Nanotechnology. 2018;29(13).
Churchman AH, Mico V, de Pablo JG, Peyman SA, Freear S, Evans SD. Combined flow-focus and self-assembly routes for the formation of lipid stabilized oil-shelled microbubbles. Microsystems & Nanoengineering. 2018;4.
Alataki A, Abou-Saleh R, McLaughlan JR, Markham AF, Evans SD, Coletta PL, et al. Developing targeted therapeutic microbubbles for enhanced epigenetic drug delivery for breast cancer. Cancer Research. 2018;78(4).
Mico V, Charalambous A, Peyman SA, Abou-Saleh RH, Markham AF, et al. Evaluation of lipid-stabilised tripropionin nanodroplets as a delivery route for combretastatin A4. Int J Pharm. 2017;526(1-2):547-555.
Kong Y, Chen J, et al. Highly fluorescent ribonuclease-A-encapsulated lead sulfide quantum dots for ultrasensitive fluorescence in vivo imaging in the second near-infrared window. Chemistry of Materials 2017, 28 (9), 3041-3050
Peyman SA, McLaughlan JR, Abou-Saleh RH, Marston G, Johnson BR, Freear S, et al. On-chip preparation of nanoscale contrast agents towards high-resolution ultrasound imaging. Lab Chip. 2016;16(4):679-687.
Ye SJ, Marston G, McLaughlan JR, Sigle DO, Ingram N, Freear S, et al. Engineering Gold Nanotubes with Controlled Length and Near-Infrared Absorption for Theranostic Applications. Advanced Functional Materials. 2015;25(14):2117-2127.
Abou-Saleh RH, Swain M, Evans SD, Thomson NH. Poly(ethylene glycol) lipid-shelled microbubbles: abundance, stability, and mechanical properties. Langmuir. 2014;30(19):5557-5563.
Bencsik M, Al-Rwaili A, Morris R, Fairhurst DJ, Mundell V, Cave G, et al. Quantitation of MRI sensitivity to quasi-monodisperse microbubble contrast agents for spatially resolved manometry. Magn Reson Med. 2013;70(5):1409-1418.
Abou-Saleh RH, Peyman SA, Critchley K, Evans SD, Thomson NH. Nanomechanics of lipid encapsulated microbubbles with functional coatings. Langmuir. 2013;29(12):4096-4103.
Peyman SA, Abou-Saleh RH, McLaughlan JR, Ingram N, Johnson BR, Critchley K, et al. Expanding 3D geometry for enhanced on-chip microbubble production and single step formation of liposome modified microbubbles. Lab Chip. 2012;12(21):4544-4552.
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