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Previous experience with intraventricular catheter connected to Rickham reservoir positioning for intrathecal drug delivery in chronic neurological disease (CLN2). Anedoctal cases of intraventricular catheter connected to Rickham reservoir positioning for intrathecal chemotherapy in selected cases of CNS malignancies.

Existing collaborations relevant to drug delivery

N/A

Publications relevant to drug delivery

Guido C, Baldari C, Maiorano G, Mastronuzzi A, Carai A, Quintarelli C, De Angelis B, Cortese B, Gigli G, Palamà IE. Nanoparticles for Diagnosis and Target Therapy in Pediatric Brain Cancers. Diagnostics (Basel). 2022 Jan 12;12(1):173. doi: 10.3390/diagnostics12010173.

Quintarelli C, Camera A, Ciccone R, Alessi I, Del Bufalo F, Carai A, Del Baldo G, Mastronuzzi A, De Angelis B. Innovative and Promising Strategies to Enhance Effectiveness of Immunotherapy for CNS Tumors: Where Are We? Front Immunol. 2021 Jun 7;12:634031. doi: 10.3389/fimmu.2021.634031. eCollection 2021.

Arnone CM, Polito VA, Mastronuzzi A, Carai A, Diomedi FC, Antonucci L, Petrilli LL, Vinci M, Ferrari F, Salviato E, Scarsella M, De Stefanis C, Weber G, Quintarelli C, De Angelis B, Brenner MK, Gottschalk S, Hoyos V, Locatelli F, Caruana I, Del Bufalo F. Oncolytic adenovirus and gene therapy with EphA2-BiTE for the treatment of pediatric high-grade gliomas. J Immunother Cancer. 2021 May;9(5):e001930. doi: 10.1136/jitc-2020-001930.