Brennan, Paul

Reader and Honorary Consultant Neurosurgeon

University of Edinburgh, NHS Lothian, UK

Surgical Neuro-Oncology

My clinical work informs my interest in developing novel strategies for delivering chemotherapy focally in management of brain tumours. This led to the collaborations with Dr Unciti-Broceta developing a palladium activated prodrug. 

Existing collaborations relevant to drug delivery

Professor Asier Unciti-Broceta, University of Edinburgh - collaboration on palladium catalyst research -

Dr Ferry Melchels, University of Heriot-Watt, polymers for drug delivery -

Publications relevant to drug delivery

Gold‐triggered uncaging chemistry in living systems. AM Pérez‐López, B Rubio‐Ruiz, V Sebastián, L Hamilton, C Adam, ...Angewandte Chemie International Edition 56 (41), 12548-12552

Bioorthogonal uncaging of the active metabolite of irinotecan by palladium‐functionalized microdevices. C Adam, AM Pérez‐López, L Hamilton, B Rubio‐Ruiz, TL Bray, D Sieger, ...Chemistry–A European Journal 24 (63), 16783-16790

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