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Prof. Frank Boury develops innovative locoregional treatments for cancer, especially glioblastoma, such as micro- and nano- drug carriers or implants (scaffolds) for entrapment of cancer cells. His expertise is thus wide and covers the fields of nano- and micromedicine formulation, physico-chemical characterization and in vitro, animal preclinical studies and clinical studies in the field of GBM carried out by renowned MDs. In addition, strong links exist with University hospitals in Angers and Nantes. 

Existing collaborations relevant to drug delivery

Universities of: Modena-Italy (Pr. G Tosi), Luxembourg-LIST, (Dr. JS Thomann), Sqantiago de Compostela (Dr. Carmen Alvarez Lorenzo), Liège-Belgium (Pr. C Jérome, Prof. Moreno Galeni), Nottingham-UK (Dr. M Zelzer), Western cape-South Africa (Dr. Admire Dube), la Plata-Argentina (Pr. G Castro), Buenos Aires (Dr. Galo Soler Ilia), Sofia-Bulgaria (Prof. I Panaïotov), 

Publications relevant to drug delivery

M. Haji Mansor, M. Najberg, A. Contini, C. Alvarez-Lorenzo, E. Garcion, C. Jérôme, F. Boury. (2018) Development of a non-toxic and non-denaturing formulation process for encapsulation of SDF-1a into PLGA/PEG-PLGA nanoparticles to achieve sustained release, Eur. J. Pharm. Biopharm. 125, 38-50.

N. Henry, J. Clouet, C. Le Visage, P. Weiss, E. Gautron, D. Renard, T. Cordonnier, F. Boury, B. Humbert, H. Terrisse, J. Guicheux, J. Le Bideau. (2017) Silica nanofibers as a new drug delivery system: a study of the protein–silica interactions, J. Mater. Chem. B 5, 2908-2920.

Z. Y. Ergul, T. Cordonnier, A. Debuigne, B. Calvignac, C. Jerome, F. Boury. (2016) Protein encapsulation and release from PEO-b-polyphosphoester templated calcium carbonate particles, Int. J. Pharm. 513 (1-2), 130-137.

Z. Y. Ergul, A. Debuigne, B. Calvignac, F. Boury, C. Jerome. (2015) Double hydrophilic polyphosphoester containing copolymers as efficient templating agents for calcium carbonate microparticles, J. Mater. Chem. B. 3, 7227-7236.

A. Swed, T. Cordonnier, A. Denarnaud, C. Boyer, J. Guicheux, P. Weiss, F. Boury. (2015) Sustained release of TGF-beta 1 from biodegradable microparticles prepared by a new green process in CO2 medium, Int. J. Pharm. 493 (1-2), 357-365.