Vaideanu, Alexandra

PhD Student

University of Cambridge, UK

My PhD focuses on engineering a drug delivery system based on gold nanomaterials for the therapy of glioblastoma multiforme. Synergy between chemo and radiotherapy mediated by gold nanoparticles is further exploited by targeting GBM tumors specifically. We employ amphiphilic peptide sequences which target neuropiln-1 highly expressed in our patient derived cell populations and exploit local delivery by direct injection at the tumor site, using novel Laser-Ablation ICP-MS and MALDI-MS imaging to determine nanoparticle distribution in relation to tumor area.

Existing collaborations relevant to drug delivery

Prof. Colin Watts - leads the newly established Brain Cancer Program at the University of Birmingham, molecular genetic heterogeneity of individual tumours

Prof. Uwe Karst - University of Muenster, Professor of Analytical Chemistry, Chemical imaging of biological tissues.

Publications relevant to drug delivery

N/A


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