Topham, Caroline

Principal Investigator

University of Salford, UK

Improving efficacy of anti-mitotic chemotherapy for treatment of medulloblastoma

We are interested in understanding how molecular heterogeneity in medulloblastoma may be linked to functional heterogeneity, in terms of sensitivity/resistance to vincristine. Through this work we have identified a potential strategy for sensitization of medulloblastoma lines using a combination treatment, but this second treatment cannot cross the blood-brain barrier. We are therefore interested in making links with researchers with expertise in modes of drug delivery to circumvent this.

Existing collaborations relevant to drug delivery

N/A

Publications relevant to drug delivery

N/A


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