Thomas, Neil

Professor of Medicinal & Biological Chemistry

University of Nottingham, UK

School of Chemistry

I am currently Head of the Biological Chemistry Theme within the School of Chemistry and Deputy Director of the Centre for Biomolecular Sciences. My research includes the development of targeted drug delivery vehicles and theranostics based on protein structures and the generation and evaluation of in vivo imaging agents utilizing fluorescence, bioluminescence and MRI modalities. These include quantum dots, BRET and FRET enzyme activated agents, apoferritin and Dps self-assembling nanocages and recombinant spider silk scaffolds.

Existing collaborations relevant to drug delivery

N/A

Publications relevant to drug delivery

Faas H, Krupa J, Taylor A, Zamberlan F, Philp C, Williams S, Johnson S, Johnson S, Pavlovskaya G, Thomas NR, Meersmann T (2019) Accelerated 19F·MRI Detection of Matrix Metalloproteinase-2/-9 through Responsive Deactivation of Paramagnetic Relaxation Enhancement, Contrast Media & Molecular Imaging, 4826520

Zamberlan F, Turyanska L, Patane A, Liu Z, Williams HEL, Fay MW, Clarke PA, Imamura Y, Jin T, Bradshaw TD, Thomas NR, Grabowska AM (2018) Stable DHLA-PEG capped PbS quantum dots: from synthesis to near-infrared biomedical imaging: Journal of Materials Chemistry B Journal of Materials Chemistry B. 6(4), 550-555

Harvey D, Bardelang P, Goodacre SL, Cockayne A, Thomas NR (2017) Antibiotic Spider Silk: Site-Specific Functionalization of Recombinant Spider Silk Using "Click" Chemistry, Advanced Materials 29(10)

Kuruppu AI, Zhang L, Collins H, Turyanska L, Thomas NR, Bradshaw TD (2015) An Apoferritin-based Drug Delivery System for the Tyrosine Kinase Inhibitor Gefitinib, Advanced Healthcare Materials. 4(18), 2816-2821


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