Perez-Garcia, Lluisa

Anne McLaren Research Fellow

University of Nottingham, UK

Pharmacy

My current interests are mainly in the field of nanobiomedicine, and include the use of metallic and inorganic nanoparticles as well as supramolecular hydrogels for drug delivery of anticancer agents, especially photosensitizers for photodynamic therapy. Also, the bio-functionalization of silicon microparticles to study, individually tag and actuate inside living cells (multiplexing materials). I was appointed as an Anne McLaren Research fellow in September 2017. 

Existing collaborations relevant to drug delivery

David Russell (University of East Anglia)

Ana Calpena (Universitat de Barcelona)

Jose Antonio Plaza (Institute of Microelectronics-CSIC) 

Publications relevant to drug delivery

Alea-Reyes ME, Penon O, García Calavia P, Marín MJ, Russell DA, Pérez-García L (2018) Synthesis and in vitro phototoxicity of multifunctional Zn(II)meso-tetrakis(4-carboxyphenyl)porphyrin-coated gold nanoparticles assembled via axial coordination with imidazole ligands.  J. Colloid Interface Sci 521, 81-90  

Limón D, Fábrega MJ, Calpena AC, Badia J, Baldoma L, Pérez-García L (2018) Multi-functional serine protease inhibitor-coated water-soluble gold nanoparticles as a novel targeted approach for the treatment of inflammatory skin diseases. Bioconjugate Chem 29, 1060−1072 

Limón D, Jiménez-Newman C, Calpena AC, González-Campo A, Amabilino DB, Pérez-García L (2017)  Microscale coiling in bis-imidazolium supramolecular hydrogel fibres induced by the release of a cationic serine protease inhibitor. Chem Comm 53, 4509-4512 

Limón D, Jiménez-Newman C, Rodrigues M, Calpena AC, González-Campo A, Amabilino DB, Pérez-García L (2017) Cationic supramolecular hydrogels for overcoming the skin barrier in drug delivery. ChemistryOpen 6, 585-598 

Penon O, Marín MJ, Russell DA, Pérez-García L (2017) Water soluble, multifunctional antibody-porphyrin gold nanoparticles for targeted photodynamic therapy. J. Colloid Interface Sci 496, 100-110 

Alea-Reyes ME, Soriano J, Mora-Espí I, Rodrigues M, Russell DA, Barrios L, Pérez-García L (2017) Amphiphilic gemini pyridinium-mediated incorporation of Zn(II)meso-tetrakis(4-carboxyphenyl)porphyrin into water-soluble gold nanoparticles for photodynamic therapy. Colloid Surfaces B, 158, 602-609 

Torras N, Agusil JP, Vázquez P, Duch M, Hernández-Pinto AM, Samitier J, de la Rosa EJ, Esteve J, Suárez T, Pérez-García L, Plaza JA (2016) Suspended planar-array chips for molecular multiplexing at the microscale. Adv. Mater 28, 1449–1454 

Patiño T, Soriano J, Amirthalingam E, Durán S, González-Campo A, Duch M, Ibáñez E, Barrios L, Plaza JA, Pérez-García L, Nogués C (2016) Polysilicon-chromium-gold intracellular chips for multi-functional biomedical applications. Nanoscale 8, 8773–8783


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