Leite, Diana

Senior Research Associate

University of Portsmouth, UK

Brain Tumour Centre

I am a Senior Research Associate at the Brain Tumour Centre, University of Portsmouth, focused on the development of a 3D in vitro model of brain tumours.

During an MSc in Biomedical Engineering, I explored the use of polymeric nanoparticles as drug carriers to the bone. Later, as a Research Assistant, I worked with a gene delivery system based on dendrimers for brain regeneration. I have recently completed a PhD dedicated to peptide nanomaterials for the treatment of brain tumours.

 

Existing collaborations relevant to drug delivery

Collaboration with Biophysics Laboratory at Johannes Kepler University (Austria) to use single-molecule force spectroscopy to evaluate binding of nanomaterials to tumour cells.

Publications relevant to drug delivery

A. Lalatsa, D.M. Leite, M.F. Figueiredo, M. O’Connor (2018) Nanotechnology in Brain Targeting, in Kesharwani, P. and Gupta, U. (Eds.) Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumours. Elsevier. 

Leite, D.M., Barbu, E., Pilkington, G., Lalatsa, A. (2015) Peptide amphiphiles in drug delivery. Current Topics in Medicinal Chemistry 15(22):2277-2289.


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